您现在的位置:食品科学网>杂志>下载

-Glucosidase inhibitor produced by an endophytic fungus, Xylariaceae sp. QGS 01 from Quercus gilva Blume

阅读:
2017-07-20 来源:食品科学网
责任编辑:食品科学
0

  作者:Anastasia Wheni Indrianingsih a,∗, Sanro Tachibana b

  关键词:Endophytic fungi; Quercus qilva Blume; -Glucosidase inhibitory activity; Xylariaceae sp.; Isocoumar

  内容:

Xylariaceae sp. QGS 01, an endophytic fungus isolated from the stem of Quercus gilva Blume showed high -glucosidase inhibitory activity. -Glucosidase inhibitor have the role as one of carbohydrate-hydrolyzing enzymes to postpone absorption of glucose in the digestive organs. The -glucosidase inhibitor constituents were isolated from the ethyl acetate extract of the mycellium of endophytic fungi Xylariaceae sp. QGS 01 using a bioassay-guided fractionation technique. Further separation and purification of the active fraction led to the isolation of constituents with strong inhibitory activities against -glucosidase: 8-hydroxy-6,7-dimethoxy-3-methylisocoumarine (1) with inhibitory concentration (IC50) values against -glucosidase from Saccharomyces cerevisiae of 41.75g/mL, while quercetin as the standard had an IC50 value of 4.80g/mL. The results of the present study showed that the endophytic fungus Xylariaceae sp. QGS 01 is potentially a rich source of antidiabetic medicine.

相关阅读

  • 来源:新京报  |  2016-05-19
    阅读:386

    中粮1元“贱卖”君顶酒庄或因巨债流拍

    4月15日,北京产权交易中心挂出“中粮旗下中国食品拟1元底价拍卖中粮君顶酒庄55%股权”的消息,引起行业一片哗然。1元拍卖的背后实则附有昂贵的“条件”,中标者需承担君顶酒庄所欠中粮3.92亿元的债务,而其实际对外欠账总额高达5亿多元。

  • 来源:新京报  |  2016-05-19
    阅读:386

    央视记者随机买8份草莓 均检出可致癌农药残留

    京华时报讯(记者常鑫),前天,央视财经频道《是真的吗》节目播出一组有关草莓的报道,称该栏目组记者随机在北京购买的8份草莓均检测出含有百菌清和乙草胺两种农药。

  • 来源:新京报  |  2016-05-19
    阅读:386

    麦当劳奶昔退役 业内分析恐因销量下挫

    曾在麦当劳中国餐厅服役近24年的奶昔昨日正式谢幕。虽然麦当劳中国方面称此举属正常产品调整,不过在业内看来,销量的不断下滑或才是此次奶昔下架的真正原因。

微博

食品科学服务号

食品科学订阅号

食品书店

食品科学

定价:25.00¥
会员价:20.00¥

合作媒体