您现在的位置:食品科学网>杂志>下载

The absorption kinetics of Antarctic krill oil phospholipid liposome in blood and the digestive tract of healthy mice by single gavage

阅读:
2020-03-31 来源:食品科学网
责任编辑:食品科学
0

  作者:Lin Li, Chengcheng Wang, Shan Jiang, Rong Li, Tiantian Zhang, Changhu Xue, Teruyoshi Yanagita, Xiaoming Jiang, Yuming Wang

  关键词:Antarctic krill oil, Phospholipid, Liposome, Single gavage, Absorption kinetics

  内容:Antarctic krill (Euphausia superba) oil has been gaining increasing attention due to its nutritional and functional potentials. Krill oil usually contains a high concentration (about 50%) of phospholipids (AKOP) rich in DHA and EPA accompanied with 30%–40% triacylglycerols. Phospholipids can be made into liposomes without emulsifiers due to its amphiphilic characteristics. However, the absorption kinetics of AKOP liposome in vivo is not clear, which restrict the molecular mechanism analysis related to its distinct bioactivities. The lipid analysis in serum, small intestinal content and wall was carried out after oral administration of AKOP liposome to illustrate its absorption kinetics in blood and the digestive tract of healthy mice by single gavage. The major type of the obtained AKOP was phosphatidylcholine, and the total contents of the DHA and EPA were 29.31%. AKOP liposome was almost completely digested in the small intestine in 1 h and the hydrolysis products could be quickly absorbed by intestinal enterocytes. The DHA in serum peaked at 2 h after administration of AKOP liposome. AKOP liposome could be quickly digested and absorbed in vivo. The obtained results might provide a scientific basis for the molecular mechanism analysis related to distinct bioactivities of Antarctic krill oil phospholipid.

相关阅读

  • 来源:新京报  |  2016-05-19
    阅读:386

    中粮1元“贱卖”君顶酒庄或因巨债流拍

    4月15日,北京产权交易中心挂出“中粮旗下中国食品拟1元底价拍卖中粮君顶酒庄55%股权”的消息,引起行业一片哗然。1元拍卖的背后实则附有昂贵的“条件”,中标者需承担君顶酒庄所欠中粮3.92亿元的债务,而其实际对外欠账总额高达5亿多元。

  • 来源:新京报  |  2016-05-19
    阅读:386

    央视记者随机买8份草莓 均检出可致癌农药残留

    京华时报讯(记者常鑫),前天,央视财经频道《是真的吗》节目播出一组有关草莓的报道,称该栏目组记者随机在北京购买的8份草莓均检测出含有百菌清和乙草胺两种农药。

  • 来源:新京报  |  2016-05-19
    阅读:386

    麦当劳奶昔退役 业内分析恐因销量下挫

    曾在麦当劳中国餐厅服役近24年的奶昔昨日正式谢幕。虽然麦当劳中国方面称此举属正常产品调整,不过在业内看来,销量的不断下滑或才是此次奶昔下架的真正原因。

微博

食品科学服务号

食品科学订阅号

食品书店

食品科学

定价:25.00¥
会员价:20.00¥

合作伙伴