领学术科研之先,创食品科技之新
—— 中国食品杂志社
期刊集群
Evaluation of renoprotective effect of Chinese chive extracts on adenine-induced chronic renal failure
来源:食品科学网 阅读量: 326 发表时间: 2019-09-25
作者: Qiang-Ming Li, Jian-Ping Luo, Li-Hua Pan, Xue-Qiang Zha∗
关键词: Chinese chive,Renoprotection,Chronic renal failure
摘要:

The renoprotective effects of Chinese chive water and ethanol extracts (CCWE and CCEE) on adenineinduced

chronic renal failure (CRF) mice were evaluated in this study. Results showed that the renal

pathological damages and the enhancement of serum creatinine and blood urea nitrogen of CRF mice

could be significantly alleviated by the treatment of CCWE, but not CCEE. When the concentration of

CCWE reached 200 mg/kg/day, the area of renal pathological damage was decreased to the 48.1% of model

group, and the levels of serum creatinine and blood urea nitrogen were decreased to the 87.7% and 83.9%

of model group, respectively. Meanwhile, it could be found that renal oxidative stress and inflammation

of CRF mice were remarkably inhibited by CCWE. These results indicated CCWE could improve the kidney

function of CRF mice via enhancing antioxidant ability and inhibiting inflammation, and was the main

renoprotective fraction of Chinese chive.

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