The polysaccharides from edible fungus showed many kinds of biological activities, including anti-tumor, immunomodulatory, anti-inflammatory, anti-diabetes, improving functional constipation activities. In particular, the immunomodulatory effects have been paid more and more attention by scholars, but there was no systematic introduction of their immunomodulatory mechanism. So, this review introduced the immunomodulatory effects and mechanism of edible fungus polysaccharides in recent years, and then the relationships between structure and immunomodulatory effect were also discussed.
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