领学术科研之先，创食品科技之新
—— 中国食品杂志社
Cordyceps militaris, belongs to Clavicipitaceae family, was investigated for its chemical compounds,
and six compounds were isolated and purified by silica gel column chromatography, Sephadex LH-20
and recrystallization, and their structures were elucidated by spectral techniques and physicochemical
properties as ergosterol (1), adenosine (2), cordycepin (3), ergosterol peroxide (4), tetracosanoic acid
2,3-dihydroxypropylester (5), mannitol (6). Procoagulant activity was screened by assaying the activated
partial thromboplastin time (APTT), prothrombin time (PT), thrombin time (TT) and fibrinogen (FIB)
in vitro. The results indicated that ergosterol, adenosine, cordycepin, ergosterol peroxide and mannitol
showed strong procoagulant activity.
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