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Benefi cial effects of Pleurotus albidus supplementation on body weight and food intake in healthy C57BL/6 mice
来源:食品科学网 阅读量: 233 发表时间: 2022-05-30
作者: Paola Quevedo da Costa, Mariana Parron Paim, Eduardo Echer dos Reis, Patrick Türck, Marli Camassola, Paulo Cavalheiro Schenkel
关键词: Blood glucose Glutathione peroxidase Insulin Pleurotus Triglycerides
摘要:

The current investigation intended to check the infl uence of Pleurotus albidus extract supplementation on body weight, food intake, glycemia, serum lipids, and oxidative stress parameters. Healthy male C57BL/6 mice were partitioned into two experimental groups: control and P. albidus. The supplementation was performed by gavage (500 mg/kg) for 20 uninterrupted days. During this period, all animals received water and food ad libitum and they had their food ingestion and body weight monitored weekly. After, mice underwent an insulin sensitivity test, followed by euthanasia and biochemical analyses. P. albidus supplementation decreased the body weight and food intake, but it did not change other parameters in healthy mice. This work showed for the fi rst time that the P. albidus extract supplementation presents a promising potential on body weight and food intake control.

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