领学术科研之先，创食品科技之新
—— 中国食品杂志社
Food allergy is one of the most important food safety problems that has attracted increasing attention.
The food allergy experimental models provide not only the accurate allergen detection and evaluation
methods but also the powerful approaches for mechanism investigations. In this paper, we reviewed the
common food allergy cell models including mast cell, basophil granulocyte and basophil, as well as the
animal models of BALB/c mouse, C3H/HeJ mouse, and BN rat. We also introduced zebrafish, a promising
model organism for investigating immunity though lacking direct applications in food allergy to date, and
focused on traumatic inflammation, bacterial infection and viral infection models. In addition, we also
summarized the clinical diagnostic research methods for food allergy. The elucidation of these topics will
help researchers to understand the characteristics and mechanisms of various models and thus select
the proper models for particular study, so as to support further investigations of food allergy.
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