领学术科研之先,创食品科技之新
—— 中国食品杂志社
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Controlled coupling and characterization of oyster (Crassostrea gigas) ferritin with gold nanostars
来源:导入 阅读量: 26 发表时间: 2025-01-24
作者: Han Li, Xiaoyu Xia, Shuzhen Cheng, Jiachen Zang, Zhenyu Wang, Xianbing Xu, Ming Du
关键词: Gold nanostars (AuNS); Oyster ferritin; Synthesis; Structure; Micro-computed tomography
摘要:

Ferritin has good thermal stability, resistance to certain acids and bases, and targeting, and has broad application prospects in the synthesis of gold nanostars (AuNS). In this study, we screened monodisperse AuNS with uniform particle size and morphology through a one-step synthesis method and coupled the synthesized AuNS with oyster ferritin (GF1). The results showed that the surface plasmon resonance (SPR) peaks of the coupled GF1@AuNS changed significantly, and the changes in infrared spectra and potential confirmed the success of the synthesis, while the microscopic morphology showed an increase in particle size and surface peak coverage. Furthermore, GF1@AuNS does not induce cell death in the 100 µmol/L range, is highly stable in physiological environments, and exhibits good X-ray attenuation in micro-computed tomography. Due to the unique functional activity of ferritin and AuNS, GF1@AuNS has potential applications in food detection and drug development in the future.

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