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A comprehensive review on mechanism of natural products against Staphylococcus aureus
来源:食品科学网 阅读量: 312 发表时间: 2022-05-30
作者: Yingying Zhao, Jinfeng Wei, Changqin Li, Adel F. Ahmed, Zhenhua Liu, Changyang Ma
关键词: Natural products; Staphylococcus aureus; Antibacterial mechanism; Enzymes; Cell wall
摘要:

The abuse of antibiotics seriously threatens the therapeutic effect. Natural products from plants, antimicrobial peptides and micro-organisms have antibacterial activity against Staphylococcus aureus. The mechanism of natural products reported in recent years on S. aureus includes six types, which are the acting on bacterial cell wall, cytomembrane, metabolic pathway, protein, nucleic acid, biofilm and quorum sensing system to achieve antibacterial effect. This article summarized the mechanism of natural products reported in recent years on S. aureus. It is found that the natural products acting on cell wall or cell wall synthesis pathway key enzymes are relatively safe and highly selective. It has the prospect of developing into medicine and provides the clue to investigate and utilize natural products in antibacterial activity.

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